منابع مشابه
Gut Immunity: A NOD to the Commensals
The gut microbiota play critical roles in intestinal function, but the mechanisms involved remain obscure. Recent studies suggest that commensal bacteria promote immune homeostasis via the innate immune receptor Nod1.
متن کاملAdaptive immunity to murine skin commensals.
The adaptive immune system provides critical defense against pathogenic bacteria. Commensal bacteria have begun to receive much attention in recent years, especially in the gut where there is growing evidence of complex interactions with the adaptive immune system. In the present study, we observed that commensal skin bacteria are recognized by major populations of T cells in skin-draining lymp...
متن کاملYeasts in the gut: from commensals to infectious agents.
BACKGROUND Controversy still surrounds the question whether yeasts found in the gut are causally related to disease, constitute a health hazard, or require treatment. METHODS The authors present the state of knowledge in this area on the basis of a selective review of articles retrieved by a PubMed search from 2005 onward. The therapeutic recommendations follow the current national and intern...
متن کاملBlurred Lines: Pathogens, Commensals, and the Healthy Gut
Detailed studies of the chickenmicrobiome have emerged in recent years, largely due to the impact of next-generation sequencing (NGS). We increasingly understand how the microbiome is important in health, in development of the gut and the immune system, and in maintenance of homeostasis. Manipulation of the microbiota directly through probiotics or antimicrobials or indirectly through feed and ...
متن کاملHost-Specific Functional Significance of Caenorhabditis Gut Commensals
The gut microbiota is an important contributor to host health and fitness. Given its importance, microbiota composition should not be left to chance. However, what determines this composition is far from clear, with results supporting contributions of both environmental factors and host genetics. To gauge the relative contributions of host genetics and environment, specifically the microbial di...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2009
ISSN: 0960-9822
DOI: 10.1016/j.cub.2008.12.027